1. The Vanishing of Amelia Earhart

Amelia Earhart wasn’t just a skilled pilot, she was an international celebrity who inspired a generation. In 1937, she and her navigator Fred Noonan disappeared while trying to circumnavigate the globe, somewhere over the vast Pacific Ocean. Despite an unprecedented search effort and numerous expeditions since, no conclusive trace of her plane has ever been found shares the New Yorker.
Theories range from running out of fuel and crashing into the ocean, to surviving a landing on a remote island like Nikumaroro. Some even speculate she was captured by the Japanese. Bones found on the island matched her description, but DNA was never confirmed. Each theory seems to answer one question but leaves three more behind. Her story endures not just because of who she was, but because we’re still waiting for that final chapter. Almost 90 years later, the silence she left behind is louder than ever adds HowStuffWorks.
2. The Lost Colony of Roanoke

When over 100 English settlers arrived on Roanoke Island in 1587, they hoped to build a new life in the New World. But when supply ships finally returned three years later, they found the settlement abandoned, with only one cryptic word—“Croatoan”—carved into a post. There were no signs of struggle, no graves, and no clear answers says Live Science.
Some believe the colonists joined a nearby Native American tribe, while others suggest they were wiped out by disease, starvation, or conflict. The “Croatoan” clue has never led to solid proof. Archaeologists have searched for decades but found little beyond speculation. It’s as if the colony was swallowed whole by history. That eerie emptiness has kept the mystery alive for centuries adds Fox News.
3. The Disappearance of the Sodder Children

On Christmas Eve 1945, the Sodder family’s home in West Virginia caught fire. George and Jennie Sodder escaped with four of their children, but five others were never seen again. The fire department didn’t arrive for hours, and no remains were ever found in the ashes. The official story claimed they died in the blaze, but nothing quite added up.
The Sodders believed their children had been kidnapped. Strange details fed the theory: a woman said she saw the kids alive a year later, and a mysterious photo mailed decades later resembled their missing son. The family even erected a billboard offering rewards for information. They never gave up hope, and the case was never officially closed. The missing children became a lifelong heartbreak, wrapped in unanswered questions.
4. The Flannan Isles Lighthouse Keepers

In 1900, three lighthouse keepers stationed on the remote Flannan Isles off Scotland vanished without a trace. When relief arrived, the lighthouse was empty, clocks were stopped, and meals were uneaten. There were no signs of foul play, but the eerie stillness felt deliberate.
Investigators believed a rogue wave may have swept them away, but that didn’t explain why their oilskins were missing or why one keeper would’ve left during a storm. Others claimed they were victims of something stranger—ghosts, sea monsters, or madness. It’s been over a century, yet the lighthouse still casts a long shadow. The image of their quiet dinner, forever interrupted, lingers like a ghost story told by the sea.
5. The Mystery of D.B. Cooper

In 1971, a man using the name Dan Cooper hijacked a plane, demanded $200,000, and parachuted into the night sky. He was never seen again. Despite one of the most extensive manhunts in U.S. history, no one knows who he was or what happened after he jumped.
A few clues surfaced over the years, like cash from the ransom found buried near a river. But leads always ran cold. He became a folk hero of sorts—cool, calm, and seemingly unstoppable. Some believe he died in the wilderness, others think he pulled off the ultimate getaway. The FBI closed the case in 2016 without answers, leaving Cooper as one of America’s most legendary ghosts.
6. The Disappearance of Malaysia Airlines Flight 370

In 2014, Malaysia Airlines Flight 370 took off with 239 people on board and never reached its destination. For days, no one knew what happened. Eventually, it was determined the plane veered far off course and likely crashed into the Indian Ocean, but the full truth remains elusive.
Debris washed ashore on distant islands, but the main wreckage has never been found. Some suspect mechanical failure, while others suggest a hijacking or even pilot sabotage. Families of the victims still seek answers, and the story continues to spark documentaries and global debate. It’s a haunting reminder of how even in the age of GPS and satellite tracking, something so big can simply disappear.
7. The Missing Crew of the Mary Celeste

In 1872, the merchant ship Mary Celeste was found drifting in the Atlantic Ocean, completely intact and stocked with supplies. But the crew was gone, leaving behind only their personal belongings and an eerie silence. The ship’s lifeboat was missing, yet there were no signs of struggle or bad weather.
Theories abound—mutiny, pirates, poisoning, even sea monsters. The ship’s cargo of alcohol could’ve leaked and sparked fear of an explosion, prompting a panicked evacuation. Still, no one knows why they never returned or where they went. The Mary Celeste became the ultimate maritime ghost ship, floating in mystery for generations.
8. The Disappearance of Harold Holt

In 1967, Australia’s Prime Minister Harold Holt went for a swim and never came back. Despite a massive search operation involving police, the navy, and even local surfers, no body was ever recovered. The ocean simply swallowed a sitting world leader.
Many believe he drowned in rough waters, but conspiracy theories quickly surfaced. Some thought he faked his death or was taken by a Chinese submarine. The absence of answers left room for wild speculation. Decades later, Holt’s vanishing still feels surreal, like something out of a political thriller that never got resolved.
9. The Disappearance of Ettore Majorana

Ettore Majorana was a brilliant Italian physicist who worked alongside legends like Enrico Fermi. In 1938, he booked a boat ticket from Palermo to Naples—and vanished without a trace. His disappearance has puzzled scientists and historians for decades.
Some thought he committed suicide, others believed he fled to a monastery or even defected to South America. Letters he sent before disappearing hinted at inner turmoil but offered no clear explanation. His mind was said to be ahead of its time, and some even speculate he feared the power of his own scientific work. Whatever the reason, he stepped into history and then out of it completely.
10. The Disappearance of Jimmy Hoffa

Jimmy Hoffa, the powerful labor union leader, vanished in 1975 after heading to a meeting with two mob associates. His car was found, but he was not. No one has seen him since, and the FBI’s search has spanned fields, homes, and even stadium foundations.
He was known to have mob ties, and most believe he was killed to prevent him from regaining power in the union. Tips have surfaced over the years, but none led to Hoffa’s body. Theories include everything from incineration to burial under a highway. Decades later, Hoffa’s name is still synonymous with “disappearance,” and his case remains one of the biggest mysteries in American crime history.
11. The Disappearance of Glenn Miller

Glenn Miller, the beloved bandleader whose swing music helped define the World War II era, vanished in 1944 during a flight to France. The plane took off over the English Channel and was never heard from again. No wreckage or bodies were ever found.
Officially, it’s believed the plane crashed due to bad weather, but conspiracy theories quickly cropped up. Some say he was on a secret mission and died under classified circumstances. Others suggest he made it to France and died later in a cover-up. The world lost not just a musician, but a symbol of American morale. His music lives on, but his last moments remain unsolved.
12. The Beaumont Children

In 1966, three siblings—Jane, Arnna, and Grant Beaumont—went to the beach near Adelaide, Australia, and never came home. Witnesses saw them playing happily, then walking off with a man. After that, nothing. No clues, no remains, no closure.
Their disappearance shocked the nation and forever changed how Australians watched their children in public. Despite thousands of tips and several persons of interest, the mystery remains. Over the decades, suspects have been investigated and even exhumed, but nothing definitive has emerged. The Beaumont case remains one of Australia’s most heartbreaking unsolved tragedies.